pentobarbital will minimize the level or influence of hydrocortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital will lessen the extent or result of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization of naloxegol with powerful CYP3A4 inducers just i